If you’re looking for a dish that combines the luxurious creaminess of Italian cuisine with the robust flavors of Mediterranean cooking, look no further than the Creamy Spinach-Artichoke Greek Chicken Alfredo Recipe. This delightful fusion brings together herb-marinated chicken breasts, pan-seared to perfection, and a luscious Alfredo sauce enriched with tender spinach, artichokes, and mushrooms. Every bite promises an explosion of savory tastes, complemented by the nutty touch of Parmesan and the vibrant freshness of lemon. The added nutritional benefit of roasted broccoli makes this meal not only indulgent but also wholesome. It’s perfect for a cozy weeknight dinner that feels like a special occasion. Whether you’re an experienced home chef or a culinary novice, this recipe is accessible and satisfying, and it is bound to become a staple in your kitchen.
Why You’ll Love This Creamy Spinach-Artichoke Greek Chicken Alfredo Recipe
- Flavor Fusion: Combines the best of Mediterranean and Italian tastes.
- Nourishing Ingredients: Packed with veggies and lean protein.
- Simple Preparation: Easy steps for a gourmet meal experience.
- Versatile: Can be enjoyed alone or with pasta, rice, or even cauliflower mash.
- Family-Friendly: A dish that everyone at the dinner table will enjoy.
Preparation Phase & Tools to Use
Before diving into cooking, you’ll want to ensure your kitchen is ready for the culinary journey ahead. Prepare a clean workspace by clearing countertops and organizing your ingredients on the cooking station. Gather essential tools such as a whisk, mixing bowls, a large skillet, a saucepan, and a sharp chef’s knife. Preheat your oven to 425°F (220°C) to accommodate the roasted broccoli. A baking sheet lined with parchment paper will streamline the roasting process, and a stovetop grill pan could add an extra depth of flavor to your chicken if you choose. Ensuring you have everything at arm’s reach will make for a smoother cooking experience.

Ingredients
- 2 large chicken breasts, boneless and skinless
- 2 tablespoons olive oil
- 1 tablespoon lemon juice
- 1 teaspoon dried oregano
- 2 garlic cloves, minced
- 0.5 teaspoon paprika
- Salt and black pepper, to taste
- 1 tablespoon unsalted butter
- 2 garlic cloves, finely minced
- 1 cup heavy cream
- 0.5 cup grated Parmesan cheese
- 0.5 cup chopped spinach
- 0.5 cup chopped artichoke hearts
- 0.5 cup sliced mushrooms (optional)
- 0.25 teaspoon ground nutmeg (optional)
- Salt and black pepper, to taste
- 2 cups broccoli florets
- 1 tablespoon olive oil
- Salt and pepper, to taste
- 0.25 teaspoon crushed red pepper flakes (optional)
Instructions
Step 1: Marinate the Chicken
Begin by whisking together olive oil, lemon juice, dried oregano, minced garlic, paprika, salt, and pepper in a bowl. Immerse the chicken breasts into this marinade, and allow them to soak up the flavors in the refrigerator for at least 30 minutes, or up to 4 hours if planning ahead. This infusion of flavors ensures each bite of chicken is tender and bursting with taste.
Step 2: Roast the Broccoli
As the chicken marinates, preheat your oven to 425°F (220°C). On a baking sheet, evenly distribute the broccoli florets. Drizzle them with olive oil, sprinkle with salt, black pepper, and if desired, a pinch of crushed red pepper flakes for heat. Roast this vibrant green addition in the oven for 20-25 minutes until the broccoli is tender and slightly caramelized at the edges.
Step 3: Sear the Chicken
Once marinated, sear your chicken breasts in a hot skillet over medium-high heat for 5-6 minutes per side. This will lock in those juices and create a beautiful golden crust. After searing, let the chicken rest before slicing it into elegantly thin slices, ensuring every piece is as flavorful as the last.
Step 4: Create the Alfredo Sauce
Set a saucepan over medium heat and begin by melting the butter. Add finely minced garlic and sauté briefly until fragrant. Introduce the mushrooms and cook them until soft. Within this savory mixture, add spinach and artichoke hearts, stirring to meld the flavors. Gradually pour in the heavy cream, simmering the concoction gently, before reducing the heat and adding the Parmesan cheese. Stir until the cheese dissolves into a creamy, thick sauce. Season the mix with nutmeg, salt, and black pepper, simmering for another 2-3 minutes.
Step 5: Serve and Enjoy
On each plate, spoon a generous portion of the Alfredo sauce, layer it with slices of the seared chicken, and serve alongside the roasted broccoli for a complete meal. Optionally, this sauce can be draped over pasta, rice, or cauliflower mash—tailored to your preference.

Variations
- Protein: Consider using shrimp or turkey for a different culinary experience.
- Vegetables: Add bell peppers or zucchini for a colorful twist.
- Spices: Amp up the taste with some rosemary or thyme in the marinade.
Cooking Notes
- Ensure the chicken is cooked to an internal temperature of 165°F for safety.
- The Alfredo sauce will thicken as it cools, so consider keeping it warm if not serving immediately.
Serving Suggestions
- Pair with a crisp white wine to enhance the creamy flavors.
- Serve with garlic bread to scoop up the luscious sauce.
Tips
- For a lighter version, use half-and-half instead of heavy cream.
- Marinate the chicken overnight to maximize flavor infusion.
Prep Time, Cook Time, Total Time
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
Nutritional Information
- Calories: Approximately 450 per serving
- Protein: 32g
- Sodium: 550mg
FAQs
Can I make this dish ahead of time?
Yes, you can prepare the chicken and sauce in advance, storing them separately. Reheat gently before serving to maintain the creamy texture of the Alfredo sauce.
Is there a substitute for artichokes?
If artichokes are not to your taste, consider substituting with sundried tomatoes or eggplant slices for an equally delightful twist.
What pasta pairs well with this Alfredo?
Fettuccine or penne are excellent pasta choices that hold the Alfredo sauce wonderfully. Zoodles can also be a healthy alternative.
How can I make this vegetarian?
Swap out the chicken for tofu or tempeh and remove the chicken marinade. Increase the portion of vegetables to continue delivering a hearty meal.
Conclusion
The Creamy Spinach-Artichoke Greek Chicken Alfredo Recipe effortlessly brings the warmth of Mediterranean cooking to your table, enriched by the classic allure of Italian flavors. This dish serves as an outstanding balance of health and indulgence, perfect for those who love creamy, vibrant meals that don’t require compromising on nutrition. Challenge your palate with this delicious balance of chicken and vegetables in a creamy sauce that pairs perfectly with various side options. Make this your weeknight go-to or your special dinner feature; either way, the rich fusion of flavors makes it a repeat favorite, inviting comments, shares, and new experiments in your kitchen.
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Creamy Spinach-Artichoke Greek Chicken Alfredo
- Total Time: 45 minutes
- Yield: 4 servings 1x
Description
A delightful fusion of chicken and creamy Alfredo sauce enriched with spinach and artichokes.
Ingredients
- 2 large chicken breasts, boneless and skinless
- 2 tablespoons olive oil
- 1 tablespoon lemon juice
- 1 teaspoon dried oregano
- 2 garlic cloves, minced
- 0.5 teaspoon paprika
- Salt and black pepper, to taste
- 1 tablespoon unsalted butter
- 2 garlic cloves, finely minced
- 1 cup heavy cream
- 0.5 cup grated Parmesan cheese
- 0.5 cup chopped spinach
- 0.5 cup chopped artichoke hearts
- 0.5 cup sliced mushrooms (optional)
- 0.25 teaspoon ground nutmeg (optional)
- 2 cups broccoli florets
- 1 tablespoon olive oil
- 0.25 teaspoon crushed red pepper flakes (optional)
Instructions
- Marinate the chicken by mixing olive oil, lemon juice, oregano, minced garlic, paprika, salt, and pepper; soak chicken for 30 minutes to 4 hours.
- Roast broccoli at 425°F for 20-25 minutes with olive oil, salt, and pepper.
- Sear marinated chicken in a skillet for 5-6 minutes per side, then let it rest before slicing.
- Make Alfredo sauce by sautéing garlic in butter, adding mushrooms, then spinach and artichokes; stir in cream and Parmesan, simmering until thick.
- Serve Alfredo sauce over sliced chicken with roasted broccoli on the side.
Notes
This dish can be made ahead of time; store chicken and sauce separately and reheat gently.
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Category: Dinner
Nutrition
- Calories: 450 kcal
- Sodium: 550 mg
- Protein: 32 g